SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12769

Signal sequence   MAPPTGVLSSLLLLVTIAGC

Length  20

Organism  Homo sapiens (Human)

UniProt ID  Q5VV43,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB12769.cif

Structure  SPKB12769.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1956.42964

Aliphatic index  156

Isoelectric point  5.922539791

Charge (pH=7)   -0.063990417

Topological polar surface area  679.56

Aromaticity  0

Average rotatable bonds  2.95

Number of hydrogen bond donors  24

Number of hydrogen bond acceptors  27

X logP energy  -5.0578

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.