SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12754

Signal sequence   MGAMAYPLLLCLLLAQLGLGAVG

Length  23

Organism  Homo sapiens (Human)

UniProt ID  Q5T848,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7EWP,

Predicted Structure ID  SPKB12754.cif

Structure  SPKB12754.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2288.89324

Aliphatic index  165.6521739

Isoelectric point  5.919503212

Charge (pH=7)   -0.064840831

Topological polar surface area  758.05

Aromaticity  0.043478261

Average rotatable bonds  3.173913043

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  29

X logP energy  -2.1501

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.