SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12748

Signal sequence   MRAARAAPLLQLLLLLGPWLEA

Length  22

Organism  Homo sapiens (Human)

UniProt ID  Q5T4B2,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB12748.cif

Structure  SPKB12748.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2416.99674

Aliphatic index  164.5454545

Isoelectric point  10.39777148

Charge (pH=7)   0.9997528

Topological polar surface area  876.82

Aromaticity  0.045454545

Average rotatable bonds  3.454545455

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  28

X logP energy  -2.17486

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.