SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12686

Signal sequence   MLMLFVFGVLLHEVSLS

Length  17

Organism  Homo sapiens (Human)

UniProt ID  Q5NDL2,

Motif  1..17



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB12686.cif

Structure  SPKB12686.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1935.41334

Aliphatic index  165.8823529

Isoelectric point  5.363507222

Charge (pH=7)   -0.909331487

Topological polar surface area  635.36

Aromaticity  0.117647059

Average rotatable bonds  3.705882353

Number of hydrogen bond donors  22

Number of hydrogen bond acceptors  24

X logP energy  -0.2082

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.