SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12575

Signal sequence   MASNNTSQRSGFSSFFCRLKTYFCNHFLCLFVLSFFPLSFRRLCL

Length  45

Organism  Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)

UniProt ID  Q59KZ1,

Motif  1..45



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB12575.cif

Structure  SPKB12575.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5338.28914

Aliphatic index  69.33333333

Isoelectric point  9.659960232

Charge (pH=7)   4.839835833

Topological polar surface area  2011.89

Aromaticity  0.222222222

Average rotatable bonds  3.777777778

Number of hydrogen bond donors  77

Number of hydrogen bond acceptors  71

X logP energy  -17.78212

Hydropathy 



Literature Information


Title  Identification and characterization of CaApe2--a neutral arginine/alanine/leucine-specific metallo-aminopeptidase from Candida albicans.

DOI  10.1111/j.1567-1364.2008.00411.x,

Publication Year  2008

PubMed ID  18637841,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.