SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12477

Signal sequence   MKMRFLGLVVCLVLWTLHSEASGGKLT

Length  27

Organism  Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

UniProt ID  Q4R4S5,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB12477.cif

Structure  SPKB12477.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2990.67664

Aliphatic index  122.5925926

Isoelectric point  9.674863725

Charge (pH=7)   2.028100418

Topological polar surface area  1096.55

Aromaticity  0.074074074

Average rotatable bonds  3.703703704

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  40

X logP energy  -6.33743

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.