SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12447

Signal sequence   MNKKKLGIRLLSLLALGGFVLANPVFA

Length  27

Organism  Streptococcus pyogenes serotype M28 (strain MGAS6180)

UniProt ID  Q48R29,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB12447.cif

Structure  SPKB12447.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2884.60584

Aliphatic index  148.1481481

Isoelectric point  11.92450937

Charge (pH=7)   3.997095887

Topological polar surface area  1057.5

Aromaticity  0.074074074

Average rotatable bonds  3.62962963

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  36

X logP energy  -5.22413

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.