SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12255

Signal sequence   MRPRGLPPLLVVLLGCWASVSA

Length  22

Organism  Homo sapiens (Human)

UniProt ID  Q2MV58,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB12255.cif

Structure  SPKB12255.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2335.89754

Aliphatic index  137.2727273

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  828.1

Aromaticity  0.045454545

Average rotatable bonds  3.136363636

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -4.48316

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.