SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12161

Signal sequence   MKLRGVSLAAGWFLLALSLWGQPAEA

Length  26

Organism  Canis lupus familiaris (Dog) (Canis familiaris)

UniProt ID  Q28247,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB12161.cif

Structure  SPKB12161.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2786.33044

Aliphatic index  120.3846154

Isoelectric point  9.695027686

Charge (pH=7)   0.999461077

Topological polar surface area  1022.38

Aromaticity  0.115384615

Average rotatable bonds  3.384615385

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  34

X logP energy  -5.09823

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.