SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12157

Signal sequence   MKENAASRVVFILLLFLSVSLLNG

Length  24

Organism  Bos taurus (Bovine)

UniProt ID  Q28172,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB12157.cif

Structure  SPKB12157.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2635.20344

Aliphatic index  158.3333333

Isoelectric point  9.695027686

Charge (pH=7)   0.999461077

Topological polar surface area  1004.71

Aromaticity  0.083333333

Average rotatable bonds  3.708333333

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  34

X logP energy  -6.26613

Hydropathy 



Literature Information


Title  Extracellular domain of prolactin receptor from bovine mammary gland: expression in Escherichia coli, purification and characterization of its interaction with lactogenic hormones.

DOI  10.1677/joe.0.1440393,

Publication Year  1995

PubMed ID  7738463,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.