SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12131

Signal sequence   MKTIIAVTIFGILTCAYA

Length  18

Organism  Meccus pallidipennis (Triatomine bug) (Triatoma pallidipennis)

UniProt ID  Q27049,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB12131.cif

Structure  SPKB12131.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1929.40654

Aliphatic index  141.1111111

Isoelectric point  8.522939048

Charge (pH=7)   0.934864135

Topological polar surface area  664.96

Aromaticity  0.111111111

Average rotatable bonds  3.388888889

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -2.6372

Hydropathy 



Literature Information


Title  Triabin, a highly potent exosite inhibitor of thrombin.

DOI  10.1074/jbc.270.48.28629,

Publication Year  1995

PubMed ID  7499380,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.