SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12017

Signal sequence   MHLRAHRTRRGKVSPTAKTKSLLHFIVLCVAGVVV

Length  35

Organism  Homo sapiens (Human)

UniProt ID  Q17RW2,

Motif  1..35



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB12017.cif

Structure  SPKB12017.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3882.74004

Aliphatic index  114

Isoelectric point  12.52423025

Charge (pH=7)   7.207838509

Topological polar surface area  1556.78

Aromaticity  0.028571429

Average rotatable bonds  3.685714286

Number of hydrogen bond donors  59

Number of hydrogen bond acceptors  53

X logP energy  -13.73322

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.