SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12003

Signal sequence   MGHLPTGIHGARRLLPLLWLFVLFKNATA

Length  29

Organism  Homo sapiens (Human)

UniProt ID  Q16827,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB12003.cif

Structure  SPKB12003.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3243.95284

Aliphatic index  127.9310345

Isoelectric point  12.51647976

Charge (pH=7)   3.179500825

Topological polar surface area  1167.06

Aromaticity  0.103448276

Average rotatable bonds  3.482758621

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  39

X logP energy  -4.84956

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.