SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB11863

Signal sequence   MKPAAREARLPPRSPGLRWALPLLLLLLRLGQILC

Length  35

Organism  Homo sapiens (Human)

UniProt ID  Q12913,

Motif  1..35



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB11863.cif

Structure  SPKB11863.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3933.91114

Aliphatic index  145.1428571

Isoelectric point  12.33427989

Charge (pH=7)   4.937473116

Topological polar surface area  1460.7

Aromaticity  0.028571429

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  52

Number of hydrogen bond acceptors  47

X logP energy  -6.71705

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.