General Information
SPKB ID SPKB11653
Signal sequence MLLLAAAFLVAFVLLLYMVSPLISP
Length 25
Organism Homo sapiens (Human)
UniProt ID Q06136,
Motif 1..25
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB11653.cif
Physicochemical Information
Molecular weight 2706.46704
Aliphatic index 191.2
Isoelectric point 6.093198033
Charge (pH=7) -0.002866115
Topological polar surface area 804.83
Aromaticity 0.12
Average rotatable bonds 3.28
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 31
X logP energy 2.4329
Hydropathy 
Literature Information
Title Tsc10p and FVT1: topologically distinct short-chain reductases required for long-chain base synthesis in yeast and mammals.
DOI 10.1194/jlr.M800580-JLR200,
Publication Year 2009
PubMed ID 19141869,
Patent ID NA,
