General Information
SPKB ID SPKB11465
Signal sequence MDYAKRIGQVGALAVVLGVGAAVTTHAIGSA
Length 31
Organism Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
UniProt ID P9WKQ1,
Motif 1..31
Activity Information
Pathway NA
Natural/Artificial Natural
Subcellular location Cell membrane
Secretion efficiency NA
Type NA
Structure Information
PDB ID NA,
Predicted Structure ID SPKB11465.cif
Physicochemical Information
Molecular weight 2997.50594
Aliphatic index 119.6774194
Isoelectric point 9.299751799
Charge (pH=7) 1.088191115
Topological polar surface area 1214.23
Aromaticity 0.032258065
Average rotatable bonds 3.129032258
Number of hydrogen bond donors 43
Number of hydrogen bond acceptors 42
X logP energy -12.74343
Hydropathy
Literature Information
Title Surface hydrolysis of sphingomyelin by the outer membrane protein Rv0888 supports replication of Mycobacterium tuberculosis in macrophages.
DOI 10.1111/mmi.13073,
Publication Year 2015
PubMed ID 26036301,
Patent ID NA,