General Information
SPKB ID SPKB11269
Signal sequence MKVSAALLCLLLMAATFSPQGLA
Length 23
Organism Homo sapiens (Human)
UniProt ID P80075,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB11269.cif
Physicochemical Information
Molecular weight 2349.93374
Aliphatic index 136.0869565
Isoelectric point 8.545189979
Charge (pH=7) 0.93571455
Topological polar surface area 824.53
Aromaticity 0.043478261
Average rotatable bonds 3.304347826
Number of hydrogen bond donors 29
Number of hydrogen bond acceptors 32
X logP energy -5.3278
Hydropathy
Literature Information
Title Complete crystal structure of monocyte chemotactic protein-2, a CC chemokine that interacts with multiple receptors.
DOI 10.1021/bi0009340,
Publication Year 2000
PubMed ID 11087354,
Patent ID NA,