SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB11068

Signal sequence   MYQRMLRCGAELGSPGGGGGGGGGGGAGGRLALLWIVPLTLSGLLGVAWG

Length  50

Organism  Homo sapiens (Human)

UniProt ID  P58400,

Motif  1..50



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB11068.cif

Structure  SPKB11068.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4755.55384

Aliphatic index  97.6

Isoelectric point  9.498709097

Charge (pH=7)   1.936924358

Topological polar surface area  1850.23

Aromaticity  0.06

Average rotatable bonds  3.06

Number of hydrogen bond donors  67

Number of hydrogen bond acceptors  63

X logP energy  -19.49849

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.