SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB11006

Signal sequence   MELTSRERGRGQPLPWELRLGLLLSVLAATLA

Length  32

Organism  Homo sapiens (Human)

UniProt ID  P55268,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB11006.cif

Structure  SPKB11006.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3548.20754

Aliphatic index  128.125

Isoelectric point  10.24533901

Charge (pH=7)   1.003296422

Topological polar surface area  1447.14

Aromaticity  0.03125

Average rotatable bonds  3.65625

Number of hydrogen bond donors  52

Number of hydrogen bond acceptors  46

X logP energy  -11.39942

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.