SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB11005

Signal sequence   MPHLMERMVGSGLLWLALVSCILTQASA

Length  28

Organism  Homo sapiens (Human)

UniProt ID  P55259,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Zymogen granule membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8XC5,

Predicted Structure ID  SPKB11005.cif

Structure  SPKB11005.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3028.69744

Aliphatic index  128.9285714

Isoelectric point  7.360093818

Charge (pH=7)   0.028690486

Topological polar surface area  1107.91

Aromaticity  0.035714286

Average rotatable bonds  3.5

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  41

X logP energy  -7.41853

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.