SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB10925

Signal sequence   MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQA

Length  38

Organism  Homo sapiens (Human)

UniProt ID  P53708,

Motif  1..38



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB10925.cif

Structure  SPKB10925.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3725.43594

Aliphatic index  85.26315789

Isoelectric point  8.524871591

Charge (pH=7)   1.812053529

Topological polar surface area  1402.76

Aromaticity  0.026315789

Average rotatable bonds  2.921052632

Number of hydrogen bond donors  50

Number of hydrogen bond acceptors  52

X logP energy  -16.10546

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.