SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB10880

Signal sequence   MFLGLGRFSRLVLWFAAFRKLLGHHGLASAKFLWCLCLLSVMSLPQQVWT

Length  50

Organism  Homo sapiens (Human)

UniProt ID  P51841,

Motif  1..50



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB10880.cif

Structure  SPKB10880.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5751.02294

Aliphatic index  119

Isoelectric point  11.55182285

Charge (pH=7)   5.055253048

Topological polar surface area  2010.23

Aromaticity  0.16

Average rotatable bonds  3.68

Number of hydrogen bond donors  75

Number of hydrogen bond acceptors  69

X logP energy  -7.60219

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.