SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB10853

Signal sequence   MASPGCLWLLAVALLPWTCASRALQHL

Length  27

Organism  Homo sapiens (Human)

UniProt ID  P50897,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB10853.cif

Structure  SPKB10853.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2922.56034

Aliphatic index  130.3703704

Isoelectric point  8.242951845

Charge (pH=7)   0.964940647

Topological polar surface area  1028.28

Aromaticity  0.074074074

Average rotatable bonds  3.222222222

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  37

X logP energy  -5.35423

Hydropathy 



Literature Information


Title  N-terminome analysis of the human mitochondrial proteome.

DOI  10.1002/pmic.201400617,

Publication Year  2015

PubMed ID  25944712,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.