SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB10734

Signal sequence   MVSAKKVPAIALSAGVSFALLRFLCLAVCLNESPG

Length  35

Organism  Homo sapiens (Human)

UniProt ID  P48169,

Motif  1..35



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7QN5,

Predicted Structure ID  SPKB10734.cif

Structure  SPKB10734.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3577.36264

Aliphatic index  128.2857143

Isoelectric point  8.821557977

Charge (pH=7)   1.875216611

Topological polar surface area  1310.39

Aromaticity  0.057142857

Average rotatable bonds  3.285714286

Number of hydrogen bond donors  47

Number of hydrogen bond acceptors  48

X logP energy  -10.44843

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.