SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB10712

Signal sequence   MWRVRKRGYFGIWSFPLIIAAVCAQ

Length  25

Organism  Homo sapiens (Human)

UniProt ID  P47870,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8FOI,

Predicted Structure ID  SPKB10712.cif

Structure  SPKB10712.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2969.60744

Aliphatic index  97.6

Isoelectric point  11.43200981

Charge (pH=7)   3.934854201

Topological polar surface area  1079.78

Aromaticity  0.2

Average rotatable bonds  3.68

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  35

X logP energy  -3.90019

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.