SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB10672

Signal sequence   MELGGPGAPRLLPPLLLLLGTGLLRA

Length  26

Organism  Homo sapiens (Human)

UniProt ID  P43681,

Motif  1..26



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB10672.cif

Structure  SPKB10672.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2639.28134

Aliphatic index  157.6923077

Isoelectric point  10.39777148

Charge (pH=7)   0.9997528

Topological polar surface area  936.99

Aromaticity  0

Average rotatable bonds  3.153846154

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -4.27386

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.