SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB10648

Signal sequence   MDVRALPWLPWLLWLLCRGGGDA

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P43234,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB10648.cif

Structure  SPKB10648.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2639.17414

Aliphatic index  123.0434783

Isoelectric point  6.272436061

Charge (pH=7)   -0.063104071

Topological polar surface area  931.71

Aromaticity  0.130434783

Average rotatable bonds  3.391304348

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  30

X logP energy  -1.72626

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.