SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB10612

Signal sequence   MARQKKMGQSVLRAVFFLVLGLLGHSHG

Length  28

Organism  Homo sapiens (Human)

UniProt ID  P42263,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6NJM,

Predicted Structure ID  SPKB10612.cif

Structure  SPKB10612.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3081.73684

Aliphatic index  107.8571429

Isoelectric point  12.53174853

Charge (pH=7)   4.179205791

Topological polar surface area  1208.86

Aromaticity  0.071428571

Average rotatable bonds  3.785714286

Number of hydrogen bond donors  43

Number of hydrogen bond acceptors  41

X logP energy  -9.52486

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.