SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB10569

Signal sequence   MKKSIGILSPGVALGMAGSAMSSKFFLVALAIFFS

Length  35

Organism  Homo sapiens (Human)

UniProt ID  P41221,

Motif  1..35



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB10569.cif

Structure  SPKB10569.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3578.39024

Aliphatic index  108.8571429

Isoelectric point  11.10307074

Charge (pH=7)   2.997099198

Topological polar surface area  1243.37

Aromaticity  0.114285714

Average rotatable bonds  3.4

Number of hydrogen bond donors  44

Number of hydrogen bond acceptors  48

X logP energy  -8.7816

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.