SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB10567

Signal sequence   MAFYSCCWVLLALTWHTSA

Length  19

Organism  Homo sapiens (Human)

UniProt ID  P41180,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  5K5S,

Predicted Structure ID  SPKB10567.cif

Structure  SPKB10567.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2203.61934

Aliphatic index  92.63157895

Isoelectric point  7.250885854

Charge (pH=7)   -0.035906456

Topological polar surface area  748.53

Aromaticity  0.210526316

Average rotatable bonds  3.315789474

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  29

X logP energy  -3.0576

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.