SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB10065

Signal sequence   MCGSALAFFTAAFVCLQNDRRGPASFLWAAWVFSLVLGLGQG

Length  42

Organism  Homo sapiens (Human)

UniProt ID  P26012,

Motif  1..42



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB10065.cif

Structure  SPKB10065.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4480.24534

Aliphatic index  93.0952381

Isoelectric point  8.231404231

Charge (pH=7)   0.874474729

Topological polar surface area  1650.5

Aromaticity  0.166666667

Average rotatable bonds  3.285714286

Number of hydrogen bond donors  60

Number of hydrogen bond acceptors  56

X logP energy  -12.63826

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.