SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB10053

Signal sequence   MKRLVCVLLVCSSAVA

Length  16

Organism  Homo sapiens (Human)

UniProt ID  P25774,

Motif  1..16



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB10053.cif

Structure  SPKB10053.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1692.16964

Aliphatic index  158.125

Isoelectric point  8.828181491

Charge (pH=7)   1.873736522

Topological polar surface area  628.2

Aromaticity  0

Average rotatable bonds  3.5

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  24

X logP energy  -4.53803

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.