SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB10046

Signal sequence   MKITCTDLVYVFILLFLNTSCVQA

Length  24

Organism  Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

UniProt ID  P25574,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6WB9,

Predicted Structure ID  SPKB10046.cif

Structure  SPKB10046.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2736.33834

Aliphatic index  137.9166667

Isoelectric point  6.062245352

Charge (pH=7)   -0.126664096

Topological polar surface area  983.27

Aromaticity  0.125

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  37

X logP energy  -5.2611

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.