General Information
SPKB ID SPKB10007
Signal sequence MTPHRLLPPLLLLLALLLAASPGGALA
Length 27
Organism Homo sapiens (Human)
UniProt ID P24592,
Motif 1..27
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB10007.cif
Physicochemical Information
Molecular weight 2733.43774
Aliphatic index 177.4074074
Isoelectric point 10.5517587
Charge (pH=7) 1.088890079
Topological polar surface area 915.8
Aromaticity 0
Average rotatable bonds 3.037037037
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 33
X logP energy -2.74743
Hydropathy
Literature Information
Title Isolation from adult human serum of four insulin-like growth factor (IGF) binding proteins and molecular cloning of one of them that is increased by IGF I administration and in extrapancreatic tumor hypoglycemia.
Publication Year 1990
PubMed ID 1697583,
Patent ID NA,