SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09889

Signal sequence   MARGLQVPLPRLATGLLLLLSVQPWAES

Length  28

Organism  Homo sapiens (Human)

UniProt ID  P22310,

Motif  1..28



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB09889.cif

Structure  SPKB09889.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3030.66514

Aliphatic index  142.8571429

Isoelectric point  10.39777148

Charge (pH=7)   0.9997528

Topological polar surface area  1146.41

Aromaticity  0.035714286

Average rotatable bonds  3.392857143

Number of hydrogen bond donors  39

Number of hydrogen bond acceptors  38

X logP energy  -7.22536

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.