SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09728

Signal sequence   MRLLWGLLWAFGLFASSLQ

Length  19

Organism  Cavia porcellus (Guinea pig)

UniProt ID  P19069,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB09728.cif

Structure  SPKB09728.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2209.67984

Aliphatic index  133.6842105

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  764.15

Aromaticity  0.210526316

Average rotatable bonds  3.631578947

Number of hydrogen bond donors  28

Number of hydrogen bond acceptors  25

X logP energy  -1.09623

Hydropathy 



Literature Information


Title  NH2-terminal sequence analysis of pro-C4, the precursor of the fourth component of guinea pig complement.

DOI  ,

Publication Year  1980

PubMed ID  7391069,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.