SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09707

Signal sequence   MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTS

Length  39

Organism  Homo sapiens (Human)

UniProt ID  P18507,

Motif  1..39



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6HUG,

Predicted Structure ID  SPKB09707.cif

Structure  SPKB09707.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4327.03234

Aliphatic index  92.30769231

Isoelectric point  9.145600227

Charge (pH=7)   0.995988437

Topological polar surface area  1589.98

Aromaticity  0.153846154

Average rotatable bonds  3.358974359

Number of hydrogen bond donors  57

Number of hydrogen bond acceptors  60

X logP energy  -14.0472

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.