SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09680

Signal sequence   MPRAPAPLYACLLGLCALLPRLA

Length  23

Organism  Homo sapiens (Human)

UniProt ID  P18084,

Motif  1..23



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB09680.cif

Structure  SPKB09680.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2424.06494

Aliphatic index  140.4347826

Isoelectric point  8.803861308

Charge (pH=7)   1.873177831

Topological polar surface area  812.39

Aromaticity  0.043478261

Average rotatable bonds  3.043478261

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  30

X logP energy  -2.77016

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.