SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09678

Signal sequence   MLPRVGCPALPLPPPPLLPLLLLLLGASGGGGGAR

Length  35

Organism  Homo sapiens (Human)

UniProt ID  P18065,

Motif  1..35



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB09678.cif

Structure  SPKB09678.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3385.21914

Aliphatic index  139.4285714

Isoelectric point  10.52640717

Charge (pH=7)   1.936002961

Topological polar surface area  1126.43

Aromaticity  0

Average rotatable bonds  2.771428571

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  41

X logP energy  -6.22456

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.