SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09534

Signal sequence   MRKSPGLSDCLWAWILLLSTLTGRSYG

Length  27

Organism  Homo sapiens (Human)

UniProt ID  P14867,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7QNE,

Predicted Structure ID  SPKB09534.cif

Structure  SPKB09534.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3025.57674

Aliphatic index  104.8148148

Isoelectric point  9.446889901

Charge (pH=7)   1.935303997

Topological polar surface area  1171.44

Aromaticity  0.111111111

Average rotatable bonds  3.555555556

Number of hydrogen bond donors  45

Number of hydrogen bond acceptors  41

X logP energy  -9.31366

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.