General Information
SPKB ID SPKB09530
Signal sequence MQHKRSRAMASPRSPFLFVLLALAVGGTANA
Length 31
Organism Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
UniProt ID P14789,
Motif 1..31
Activity Information
Pathway NA
Natural/Artificial Natural
Subcellular location Extracellular environment
Secretion efficiency NA
Type NA
Structure Information
PDB ID NA,
Predicted Structure ID SPKB09530.cif
Physicochemical Information
Molecular weight 3298.91834
Aliphatic index 88.38709677
Isoelectric point 12.80742811
Charge (pH=7) 4.088588423
Topological polar surface area 1326.24
Aromaticity 0.064516129
Average rotatable bonds 3.419354839
Number of hydrogen bond donors 47
Number of hydrogen bond acceptors 45
X logP energy -13.79189
Hydropathy
Literature Information
Title A substitution at His-120 in the LasA protease of Pseudomonas aeruginosa blocks enzymatic activity without affecting propeptide processing or extracellular secretion.
DOI 10.1128/jb.178.22.6608-6617.1996,
Publication Year 1996
PubMed ID 8932318,
Patent ID NA,