SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09399

Signal sequence   MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRG

Length  35

Organism  Homo sapiens (Human)

UniProt ID  P12107,

Motif  1..35



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB09399.cif

Structure  SPKB09399.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4345.04984

Aliphatic index  66.85714286

Isoelectric point  11.47875458

Charge (pH=7)   3.001377716

Topological polar surface area  1703.33

Aromaticity  0.2

Average rotatable bonds  3.914285714

Number of hydrogen bond donors  64

Number of hydrogen bond acceptors  54

X logP energy  -10.39802

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.