General Information
SPKB ID SPKB09387
Signal sequence MTPTGAGLKATIFCILTWVSLTAG
Length 24
Organism Mus musculus (Mouse)
UniProt ID P11859,
Motif 1..24
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB09387.cif
Physicochemical Information
Molecular weight 2452.95264
Aliphatic index 105.8333333
Isoelectric point 8.545189979
Charge (pH=7) 0.93571455
Topological polar surface area 887.02
Aromaticity 0.083333333
Average rotatable bonds 3.125
Number of hydrogen bond donors 33
Number of hydrogen bond acceptors 34
X logP energy -7.4298
Hydropathy
Literature Information
Title A redox switch in angiotensinogen modulates angiotensin release.
DOI 10.1038/nature09505,
Publication Year 2010
PubMed ID 20927107,
Patent ID NA,