SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09331

Signal sequence   MRGARGAWDFLCVLLLLLRVQTGSS

Length  25

Organism  Homo sapiens (Human)

UniProt ID  P10721,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  2EC8,

Predicted Structure ID  SPKB09331.cif

Structure  SPKB09331.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2763.31464

Aliphatic index  124.8

Isoelectric point  10.43741523

Charge (pH=7)   1.936446134

Topological polar surface area  1104.29

Aromaticity  0.08

Average rotatable bonds  3.64

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  36

X logP energy  -8.89889

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.