SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09328

Signal sequence   MKVISLFILVGFIGEFQSFSSA

Length  22

Organism  Homo sapiens (Human)

UniProt ID  P10643,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8B0F,

Predicted Structure ID  SPKB09328.cif

Structure  SPKB09328.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2420.89214

Aliphatic index  119.5454545

Isoelectric point  6.408795646

Charge (pH=7)   -0.000535612

Topological polar surface area  861.75

Aromaticity  0.181818182

Average rotatable bonds  3.636363636

Number of hydrogen bond donors  30

Number of hydrogen bond acceptors  31

X logP energy  -4.6433

Hydropathy 



Literature Information


Title  The structure of human complement component C7 and the C5b-7 complex.

DOI  ,

Publication Year  1988

PubMed ID  3335508,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.