SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09236

Signal sequence   MRFFHPLYLLLLLLTVLVLISA

Length  22

Organism  Danio rerio (Zebrafish) (Brachydanio rerio)

UniProt ID  P0DMC2,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB09236.cif

Structure  SPKB09236.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2586.30364

Aliphatic index  208.1818182

Isoelectric point  9.351184298

Charge (pH=7)   1.088039665

Topological polar surface area  816.9

Aromaticity  0.136363636

Average rotatable bonds  3.681818182

Number of hydrogen bond donors  29

Number of hydrogen bond acceptors  29

X logP energy  2.66717

Hydropathy 



Literature Information


Title  Toddler: an embryonic signal that promotes cell movement via Apelin receptors.

DOI  10.1126/science.1248636,

Publication Year  2014

PubMed ID  24407481,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.