SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09146

Signal sequence   MRYIRQLCCVSLLCLSGSAVA

Length  21

Organism  Escherichia coli (strain K12)

UniProt ID  P0ADE4,

Motif  1..21



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB09146.cif

Structure  SPKB09146.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2286.81224

Aliphatic index  130

Isoelectric point  8.513867957

Charge (pH=7)   1.811203115

Topological polar surface area  893.13

Aromaticity  0.047619048

Average rotatable bonds  3.571428571

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  33

X logP energy  -8.43226

Hydropathy 



Literature Information


Title  Discovery of an archetypal protein transport system in bacterial outer membranes.

DOI  10.1038/nsmb.2261,

Publication Year  2012

PubMed ID  22466966,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.