SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09126

Signal sequence   MAGPATQSPMKLMALQLLLWHSALWTVQEA

Length  30

Organism  Homo sapiens (Human)

UniProt ID  P09919,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB09126.cif

Structure  SPKB09126.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3323.97714

Aliphatic index  104.3333333

Isoelectric point  7.549726882

Charge (pH=7)   0.090373479

Topological polar surface area  1223.41

Aromaticity  0.066666667

Average rotatable bonds  3.5

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  44

X logP energy  -7.657

Hydropathy 



Literature Information


Title  Extracellular domain of granulocyte-colony stimulating factor receptor. Interaction with its ligand and identification of a domain in close proximity of ligand-binding region.

DOI  10.1006/abbi.1995.0047,

Publication Year  1995

PubMed ID  8554326,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.