SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09099

Signal sequence   MPPSGLRLLPLLLPLLWLLVLTPSRPAAG

Length  29

Organism  Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)

UniProt ID  P09533,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB09099.cif

Structure  SPKB09099.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3105.90514

Aliphatic index  164.8275862

Isoelectric point  12.50010931

Charge (pH=7)   1.997977677

Topological polar surface area  1025.66

Aromaticity  0.034482759

Average rotatable bonds  3.103448276

Number of hydrogen bond donors  34

Number of hydrogen bond acceptors  36

X logP energy  -2.15536

Hydropathy 



Literature Information


Title  Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide.

DOI  10.1128/mcb.8.10.4162-4168.1988,

Publication Year  1988

PubMed ID  3185545,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.