SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB09051

Signal sequence   MKAPAVLAPGILVLLFTLVQRSNG

Length  24

Organism  Homo sapiens (Human)

UniProt ID  P08581,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7MO7,

Predicted Structure ID  SPKB09051.cif

Structure  SPKB09051.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2509.09164

Aliphatic index  146.25

Isoelectric point  11.65177567

Charge (pH=7)   1.997685954

Topological polar surface area  929.6

Aromaticity  0.041666667

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -5.96973

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.